Society For Risk Analysis Annual Meeting 2017

Session Schedule & Abstracts

* Disclaimer: All presentations represent the views of the authors, and not the organizations that support their research. Please apply the standard disclaimer that any opinions, findings, and conclusions or recommendations in abstracts, posters, and presentations at the meeting are those of the authors and do not necessarily reflect the views of any other organization or agency. Meeting attendees and authors should be aware that this disclaimer is intended to apply to all abstracts contained in this document. Authors who wish to emphasize this disclaimer should do so in their presentation or poster. In an effort to make the abstracts as concise as possible and easy for meeting participants to read, the abstracts have been formatted such that they exclude references to papers, affiliations, and/or funding sources. Authors who wish to provide attendees with this information should do so in their presentation or poster.

Common abbreviations

Symposium: Commercializing Nanoscale Materials: Occupational Safety and Health through Risk Assessment and Risk Management

Room: Salon D   1:30 pm–3:00 pm

Chair(s): Debra Kaden, James Ede

Sponsored by Emerging Nanaoscale Materials and Occupational Health and Safety Specialty Groups

Nanomaterials continue their entry into commerce, innovating diverse ranges of products with their unique attributes and reshaping markets in the process. The road to successful commercialization of nanomaterials has required industry to assess and manage their potential risks. Although knowledge about the risks associated with nanomaterials is still evolving, industry and governmental organizations have been proactive and adopted emerging risk assessment frameworks to assess and manage risk in the workplace. This symposium will highlight the risk assessment and risk management approaches utilized by industry and governmental organizations to safely commercialize nanomaterials.

M3-D.1  1:30 pm  Occupational Safety and Health of Nanoscale Materials. Howard J*; US Government

Abstract: Occupational Safety and Health of Nanoscale Materials John Howard Risk characterization of a new technology to quickly determine if it raises safety and health issues for workers should be a priority for occupational health researchers and practitioners. Engineered nanomaterials and devices demonstrate novel size-dependent properties and behavior and hold great promise in many areas of benefit to society, such as new lightweight but stronger materials, new pharmaceuticals, enhanced water filtration, and advances in regenerative medicine. The challenge of nanotechnology from a risk perspective is 2-fold. First, does the nature of engineered nanomaterials present occupational safety and health hazards? If so, how can the benefits of nanomaterials be realized while proactively minimizing or eliminating the potential risks? NIOSH has identified 10 critical topic areas to guide in addressing knowledge gaps, developing strategies, and providing recommendations. These ten areas are: toxicity; risk assessment; epidemiology and surveillance; engineering controls and PPE; measurement methods; exposure assessment; fire and explosion safety; recommendations and guidance; global collaborations; and applications. Applications of nanotechnology is moving faster than the knowledge base about risk can be built. For instance, additive manufacturing is an increasingly prominent part of modern industry due to its utility in product development and precision manufacturing, with further growth in applications and adoption expected in coming years. A key component in additive manufacturing is the use of nanoscale metal powders. Although the occupational health implications of advanced manufacturing involving nanomaterials are not yet clearly understood, it is prudent to take precautions to protect workers until the risks can be fully characterized.

M3-D.2  1:50 pm  An EH&S Approach for Commercialization of Novel Forms of Nanocellulose. Nelson K*; American Process

Abstract: American Process Inc. (API) is the world’s first company to produce and market five different varieties of nanocellulose products with tailored morphologies and surface properties to enhance the performance of a wide variety of materials across various industries. API’s BioPlus™ nanocellulose products are manufactured using a low cost, patented process that is demonstrated at their fully-integrated Thomaston Biorefinery plant along with lignocellulosic sugars, fuels and chemicals co-products. This presentation will discuss our EH&S approach, including toxicity testing and partnership with NIOSH, for commercialization of a variety of novel forms of nanocellulose. Nanocellulose is a versatile material with a vast array of commercial applications including composites and foams for automotive, aerospace, and building construction, viscosity modifiers for cosmetics and oil drilling fluids, and high performance fillers for paper, packaging, paints, and plastics. Nanocellulose is renewable, biodegradable, biocompatible and as strong as Kevlar™. Reuter’s recently named nanocellulose as one of ten innovations that will transform the world by 2025. The US USDA estimates that global production of nanocellulose could reach 34 million tons per year in the coming decades. API has been granted 8 patents and over 250 patents pending in the nanocellulose field encompassing production methods, composition, drying, redispersion, composition, and end-use applications.

M3-D.3  2:10 pm  Practical considerations for the assessment and control of exposures to engineered nanomaterials in the secondary industry. Maberti S*; ExxonMobil Biomedical Sciences Inc.

Abstract: Neat engineered nanomaterials (ENM) are used in production processes for the formulation of intermediate and finished products (i.e. additives, composites, coatings, building materials). Handling and use of these products in the secondary industry entails manipulation, mixing, spraying, abrading, cutting, etc., which can yield occupational exposures that have not yet been well characterized, as they consist of materials different from the bulk ENMs. Studies evaluating releases from nanoenabled products show three release scenarios: particles of the carrier matrix, particles with carrier matrix and ENM, or ENM alone. Released particles may be agglomerated or severed from the bulk. Given the relative small percentage of ENM in the product, safety information might not report the potential for exposure to ENM released during the handling or use of these products. However, use in the industrial scale may lead to chronic exposures to low-levels of neat, agglomerated, or severed ENMs. Industrial hygienists must rely not only is SDS information, but on understanding of the processes that give rise to the exposure to propose appropriate controls. A practical screening approach is proposed to assess the potential release during use of nanoenabled materials and determine if additional controls are required for different stages of use.

M3-D.4  2:30 pm  Method Development for Measuring and Assessing Exposure to Nanomaterials in the Workplace. Shatkin JA*, Foster EJ, Peters TF; Vireo Advisors, LLC

Abstract: This talk will present a collaboration formed to develop methods for assessing workplace exposure to nanocellulose, to allow commercial entities to ensure they are addressing worker exposure while manufacturing nanocellulose and downstream products. Significant efforts are underway to develop nanocellulose materials with a wide range of applications including paper and packaging, coatings, absorbents, viscosity modifiers, and a diversity of composite materials. However, conventional forms of cellulose are known irritants when inhaled by workers. While the data are thin regarding health effects associated with exposure to the nano-forms of cellulose, we do know that, for a given mass concentration exposure to many other materials, adverse health effects can be greater when the material occurs as nanoparticles rather than larger ones because of the increased surface area and ability to penetrate deeper into the lung. To adequately assess and manage risk in this nascent industry, we need validated methods to detect whether, and to what extent, nanocellulose exposures may occur in the workplace. Such methods are not available because the novel detection methods that have emerged for quantitative analysis of other nanoscale materials are not suited for nanocellulose, which occurs as small organic particles with high aspect ratio (length / diameter) and at low concentrations. This presentation will discuss the process of developing the methods, present current data, and describe how the work will be developed into a standard measurement method.

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